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Nasim Kassam

Brigham and Women's Hospital

23

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7164

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Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity

2018 Journal of Immunology
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Blockade of Tim-3 binding to phosphatidylserine and CEACAM1 is a shared feature of anti-Tim-3 antibodies that have functional efficacy

2018 OncoImmunology
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Cutting edge: TIGIT has T cell-intrinsic inhibitory functions.

2011 Journal of Immunology
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Adaptive autoimmunity and Foxp3-based immunoregulation in zebrafish.

2010 PLOS ONE
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NEGATIVE IMMUNE REGULATOR TIM-3 IS OVEREXPRESSED ON INTRAHEPATIC AND PERIPHERAL T CELLS IN CHRONIC HCV INFECTION AND ITS BLOCKADE RESCUES DYSFUNCTIONAL CD4+AND CD8+T CELLS

2009
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Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

2009 Journal of Virology
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TIM-3 is Expressed on Activated Human CD4+ T Cells and Regulates Th1 and Th17 Cytokines

2009 European Journal of Immunology
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TIM-4 Expressed on APCs Induces T Cell Expansion and Survival

2008 Journal of Immunology
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TIM-3 is a Negative Regulator of Human Th1 Cells

2007 Clinical Immunology
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Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells.

2007 Science
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Citations (527)