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Yongquan Hou
Yongquan Hou
Merck & Co.
Chemistry
Biochemistry
In vivo
Ligand efficiency
Pharmacokinetics
2
Papers
12
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0
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MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation
2017
Bioorganic & Medicinal Chemistry Letters
Andrew M. Haidle
Kaleen Konrad Childers
Anna A. Zabierek
Jason D. Katz
James P. Jewell
Yongquan Hou
Michael D. Altman
Alexander A. Szewczak
Dapeng Chen
Andreas Harsch
Mansuo Hayashi
Lee Warren
Michael Hutton
Hugh Nuthall
Matt G. Stanton
Ian W. Davies
Ben Munoz
Alan B. Northrup
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Citations (4)
Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors
2017
Bioorganic & Medicinal Chemistry Letters
Jason D. Katz
Andrew M. Haidle
Kaleen Konrad Childers
Anna A. Zabierek
James P. Jewell
Yongquan Hou
Michael D. Altman
Alexander A. Szewczak
Dapeng Chen
Andreas Harsch
Mansuo Hayashi
Lee Warren
Michael Hutton
Hugh Nuthall
Hua-Poo Su
Sanjeev Munshi
Matt G. Stanton
Ian W. Davies
Ben Munoz
Alan B. Northrup
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Citations (8)
1