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L. Van Deemter

Netherlands Cancer Institute

14

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7363

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Thiopurine Metabolism and Identification of the Thiopurine Metabolites Transported by MRP4 and MRP5 Overexpressed in Human Embryonic Kidney Cells

2002 Molecular Pharmacology
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Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport.

2000 British Journal of Cancer
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Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug

1999 British Journal of Pharmacology
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Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

1998 Journal of Clinical Investigation
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Transport of glutathione A conjugates by the multifrug resistance protein 1

1997 FEBS Letters
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Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.

1996 Journal of Clinical Investigation
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Citations (247)
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

1996 Journal of Clinical Investigation
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Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1995 Journal of Clinical Investigation
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Multidrug resistance and the role of P-glycoprotein knockout mice

1995 European Journal of Cancer
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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1994 Cell
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Citations (2051)