author-photo

John R. Fulghum

Vertex Pharmaceuticals

16

Papers

915

Citations

Citation Trend

Filter By

Papers (16) Sort By

Journal Conference Others

Nonstructural Protein 5A (NS5A) and Human Replication Protein A Increase the Processivity of Hepatitis C Virus NS5B Polymerase Activity In Vitro

2015 Journal of Virology
Show All
- Source
- Cite
- Save
Citations (8)
E. coli and insect cell expression, automated purification and quantitative analysis.

2009 Methods of Molecular Biology
Show All
- Source
- Cite
- Save
Citations (4)
Screening factors effecting a response in soluble protein expression: Formalized approach using design of experiments

2006 Analytical Biochemistry
Show All
- Source
- Cite
- Save
Citations (51)
Nucleotide-binding Domains of Cystic Fibrosis Transmembrane Conductance Regulator, an ABC Transporter, Catalyze Adenylate Kinase Activity but Not ATP Hydrolysis

2006 Journal of Biological Chemistry
Show All
- Source
- Cite
- Save
Citations (23)
In Vitro Studies of Cross-resistance Mutations against Two Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061

2005 Journal of Biological Chemistry
Show All
- Source
- Cite
- Save
Citations (204)
In Vitro Resistance Studies of Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061 STRUCTURAL ANALYSIS INDICATES DIFFERENT RESISTANCE MECHANISMS

2004 Journal of Biological Chemistry
Show All
- Source
- Cite
- Save
Citations (272)
High-throughput screening for soluble recombinant expressed kinases in Escherichia coli and insect cells

2004 Protein Expression and Purification
Show All
- Source
- Cite
- Save
Citations (70)
59 VX-950, a novel HCV protease inhibitor, retains potency against BILN-2061 resitant replicon cells: Computational analysis indicates that resistance develops via different mechanisms

2004 Journal of Hepatology
Show All
- Source
- Cite
- Save
Citations (1)
1000 VX-950, a HCV protease inhibitor, retains potency against BILN-2061 resistant replicon cells

2003 Hepatology
Show All
- Source
- Cite
- Save
Citations (2)
Crystal Structure of MAPKAP2

2002
Show All
- Source
- Cite
- Save
Citations (0)