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Hisashi Harada

Virginia Commonwealth University

47

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Targeting Stress-Response Pathways and Therapeutic Resistance in Head and Neck Cancer

2021
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FOSL1 promotes metastasis of head and neck squamous cell carcinoma through super-enhancer-driven transcription program.

2021 Molecular Therapy
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Androgen-deprivation induced senescence in prostate cancer cells is permissive for the development of castration-resistance but susceptible to senolytic therapy.

2021 Biochemical Pharmacology
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Clearance of therapy‐induced senescent tumor cells by the senolytic ABT‐263 via interference with BCL‐X L ‐BAX Interaction

2020 Molecular Oncology
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Combination of fenretinide and ABT-263 induces apoptosis through NOXA for head and neck squamous cell carcinoma treatment

2019 PLOS ONE
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Tumor cell escape from therapy-induced senescence

2019 Biochemical Pharmacology
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Abstract 901: Elimination of senescent tumor cells by ABT263 interferes with proliferative recovery and provides a two-hit therapeutic approach

2019 Cancer Research
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Abstract B31: A protein synthesis switch underlies initial survival of EGFR-mutant lung cancer to EGFR inhibitors

2018 Clinical Cancer Research
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Abstract B31: A protein synthesis switch underlies initial survival of EGFR-mutant lung cancer to EGFR inhibitors

2018 Clinical Cancer Research
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P2.13-35 Inhibition of H3K27 Demethylation is Toxic in Poorly Differentiated Small Cell Lung Cancer

2018 Journal of Thoracic Oncology
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