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Julian Downward

London Research Institute
Francis Crick Institute
Lincoln's Inn

368

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45461

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Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry

2021 bioRxiv
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Abstract LB124: APOBEC3B fuels evolution of resistance during targeted cancer therapy

2021 Cancer Research
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Characterisation of tumour immune microenvironment remodelling following oncogene inhibition in preclinical studies using an optimised imaging mass cytometry workflow

2021 bioRxiv
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Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers

2021 Nature Communications
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Quantitative proteomic analysis in ATII cells reveals the different capacities of RAS and TGF-β to induce EMT

2021
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JunD, not c-Jun, is the AP-1 transcription factor required for Ras-induced lung cancer

2021 JCI insight
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Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry.

2021 Nature Communications
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Oncogenic RAS activity predicts response to chemotherapy and outcome in lung adenocarcinoma

2021 bioRxiv
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Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.

2021 Science Translational Medicine
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Therapeutic KRASG12C inhibition drives effective interferon-mediated anti-tumour immunity in immunogenic lung cancers

2021 bioRxiv
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