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Melissa A. Kotterman

Helen Wills Neuroscience Institute

10

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Viral Vector Technologies and Strategies: Improving on Nature.

2021 International Ophthalmology Clinics
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Identification and Characterization of a Novel AAV Capsid and Product for the Treatment of Cystic Fibrosis

2021
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P1516Novel cardiotropic AAV variant C102 vectors show superior gene delivery & reduced immunogenicity in non-human primates, transduction of human cardiomyocytes, & correction of Fabry disease phenotype

2019 European Heart Journal
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Towards A DNA-Directed RNA Interference (ddRNAi) Therapy Delivered Intravitreally Using a Novel AAV Capsid to Treat Choroidal Neovascularization (CNV)

2017 Investigative Ophthalmology & Visual Science
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Novel AAV Variants Show Superior Gene Delivery in Human Retinal Cell Models

2017 Investigative Ophthalmology & Visual Science
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Viral Vectors for Gene Therapy: Translational and Clinical Outlook

2015 Annual Review of Biomedical Engineering
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261. Directed Evolution of an Antibody-Evading Cardiac Tropic AAV Vector

2015 Molecular Therapy
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Enhanced cellular secretion of AAV2 by expression of foreign viral envelope proteins

2015 Biochemical Engineering Journal
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Enhanced selective gene delivery to neural stem cells in vivo by an adeno-associated viral variant.

2015 Development
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Engineering adeno-associated viruses for clinical gene therapy

2014 Nature Reviews Genetics
- Melissa A. Kotterman
- David V. Schaffer
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