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Derek Cole
Derek Cole
Takeda Pharmaceutical Company
Biochemistry
Chemistry
Kinase
Biology
Stereochemistry
5
Papers
59
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Structure-guided optimization of a novel class of ASK1 inhibitors with increased sp3 character and an exquisite selectivity profile
2020
Bioorganic & Medicinal Chemistry Letters
Simone V. Bigi-Botterill
Anthony Ivetac
Erica L. Bradshaw
Derek Cole
Douglas R. Dougan
Jacques Ermolieff
Petro Halkowycz
Ben Johnson
Christopher Mcbride
Jason Pickens
Mark Sabat
Steven Swann
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Citations (3)
Structure-based drug design of novel ASK1 inhibitors using an integrated lead optimization strategy
2017
Bioorganic & Medicinal Chemistry Letters
Tony Gibson
Benjamin Johnson
Andrea Fanjul
Petro Halkowycz
Douglas R. Dougan
Derek Cole
Steven Swann
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Citations (12)
Nonpeptide BACE1 Inhibitors: Design and Synthesis
2011
Derek Cole
Matthew Gregory Bursavich
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Citations (2)
Identification and SAR of a new series of thieno[3,2-d]pyrimidines as Tpl2 kinase inhibitors
2011
Bioorganic & Medicinal Chemistry Letters
Yike Ni
Ariamala Gopalsamy
Derek Cole
Yonghan Hu
Rajiah Aldrin Denny
Manus Ipek
Julie Liu
Julie Lee
J. Perry Hall
Michael Luong
Jean-Baptiste Telliez
Lih Ling Lin
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Citations (25)
Discovery of indazoles as inhibitors of Tpl2 kinase.
2011
Bioorganic & Medicinal Chemistry Letters
Yonghan Hu
Derek Cole
Rajiah Aldrin Denny
David R. Anderson
Manus Ipek
Yike Ni
Xiaolun Wang
Suvit Thaisrivongs
Timothy Chamberlain
J. Perry Hall
Julie Liu
Michael Luong
Lih Ling Lin
Jean-Baptiste Telliez
Ariamala Gopalsamy
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Citations (17)
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