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Larry P. Feigen

G. D. Searle & Company

26

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553

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Aminopeptidase resistant Arg-Gly-Asp analogs are stable in plasma and inhibit platelet aggregation.

2009 International Journal of Peptide and Protein Research
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Protective Effect of Oral Xemilofiban in Arterial Thrombosis in Dogs Increased Activity in Combination With Aspirin

1998 Circulation
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Assessment of platelet function assays

1998 American Heart Journal
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Thrombosis triggered by severe arterial lesions is inhibited by oral administration of a glycoprotein IIb/IIIa antagonist

1997 European Journal of Clinical Investigation
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The Amino-terminal One-third of Defines the Ligand Recognition Specificity of Integrin

1996 Journal of Biological Chemistry
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Citations (69)
A mimetic of the RGDF-peptide [arginine-glycine-aspartic acid-phenylalanine] blocks aggregation and flow-induced platelet deposition on severely injured stenotic arterial wall. Effects on different animal models and in humans

1996 Thrombosis Research
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The amino-terminal one-third of alpha IIb defines the ligand recognition specificity of integrin alpha IIb beta 3.

1996 Journal of Biological Chemistry
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The Protective Dose of the Potent GPIIb/IIIa Antagonist SC-54701A Is Reduced When Used in Combination With Aspirin and Heparin in a Canine Model of Coronary Artery Thrombosis

1996 Circulation
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Extended Inhibition of Platelet Aggregation With the Orally Active Platelet Inhibitor SC-54684A

1995 Circulation
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Design and synthesis of novel RGD analogs using synthetic sweetener models: Implication for sweet taste receptors

1995
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