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Thomas C. Roberts

University of Oxford
Scripps Research Institute
Discovery Institute

65

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1785

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Enhancing the Therapeutic Potential of Extracellular Vesicles Using Peptide Technology.

2022 Methods of Molecular Biology
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Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle.

2021 Biomaterials
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GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain.

2021 Nature Communications
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Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles

2021 Nature Biomedical Engineering
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Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity.

2021 Science Advances
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Molecular correction of Duchenne muscular dystrophy by splice modulation and gene editing.

2021 RNA Biology
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Fine Tuning of Phosphorothioate Inclusion in 2'-O-Methyl Oligonucleotides Contributes to Specific Cell Targeting for Splice-Switching Modulation.

2021 Frontiers in Physiology
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GAPDH controls extracellular vesicle biogenesis and enhances therapeutic potential of EVs in silencing the Huntingtin gene in mice via siRNA delivery

2020 bioRxiv
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Advances in oligonucleotide drug delivery

2020 Nature Reviews Drug Discovery
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Engineering of extracellular vesicles for display of protein biotherapeutics

2020 bioRxiv
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