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Barbara Thomas
Barbara Thomas
Amgen
KRAS
Toxicity
Pharmacology
Nephrotoxicity
Chemistry
2
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2
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Mercapturate pathway metabolites of sotorasib, a covalent inhibitor of KRASG12C, are associated with renal toxicity in the Sprague Dawley rat.
2021
Toxicology and Applied Pharmacology
Jonathan Werner
Rhian Davies
Jan L. Wahlstrom
Upendra P. Dahal
Min Jiang
Jonathan Stauber
Benjamin David
William Siska
Barbara Thomas
Katsu Ishida
W. Griffith Humphreys
J. Russell Lipford
Thomas M. Monticello
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Citations (2)
Nonclinical Safety Profile of Sotorasib, a KRASG12C-Specific Covalent Inhibitor for the Treatment of KRAS p.G12C-Mutated Cancer:
2021
International Journal of Toxicology
Katsu Ishida
Jonathan Werner
Rhian Davies
Fan Fan
Barbara Thomas
Jan Wahlstrom
James Russell Lipford
Thomas M. Monticello
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