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Kristen E. Mengwasser

Brigham and Women's Hospital

8

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2053

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Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

2019 Molecular Cell
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Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

2019 Cell Reports
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Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover

2016 Genes & Development
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Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome

2013 Cell
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Crystal structure of EGFR kinase domain T790M mutation in compex with HKI-272

2008
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Crystal structure of EGFR kinase domain T790M mutation in complex with AEE788

2008
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The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

2008 Proceedings of the National Academy of Sciences of the United States of America
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Citations (1428)
Crystal structure of EGFR kinase domain T790M mutation

2008
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