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Ann-Beth Nørholm
Ann-Beth Nørholm
Isothermal titration calorimetry
Ligand (biochemistry)
Allosteric regulation
Chemistry
Benzothiadiazine
3
Papers
62
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Positive Allosteric Modulators of 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors Belonging to 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-pyridothiadiazine Dioxides and Diversely Chloro-Substituted 4-Cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides
2014
Journal of Medicinal Chemistry
Pierre Francotte
Ann-Beth Nørholm
Taru Deva
Lars Olsen
Karla Frydenvang
Eric Goffin
Pierre Fraikin
Pascal De Tullio
Sylvie Challal
Jean-Yves Thomas
Fabrice Iop
Caroline Louis
Iuliana Botez-Pop
Pierre Lestage
Laurence Danober
Jette S. Kastrup
Bernard Pirotte
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Citations (21)
Thermodynamic Characterization of New Positive Allosteric Modulators Binding to the Glutamate Receptor A2 Ligand-Binding Domain: Combining Experimental and Computational Methods Unravels Differences in Driving Forces
2014
Journal of Chemical Information and Modeling
Ann-Beth Nørholm
Pierre Francotte
Eric Goffin
Iuliana Botez
Laurence Danober
Pierre Lestage
Bernard Pirotte
Jette S. Kastrup
Lars Olsen
Chris Oostenbrink
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Synthesis, pharmacological and structural characterization, and thermodynamic aspects of GluA2-positive allosteric modulators with a 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide scaffold.
2013
Journal of Medicinal Chemistry
Ann-Beth Nørholm
Pierre Francotte
Lars Olsen
Christian Krintel
Karla Frydenvang
Eric Goffin
Sylvie Challal
Laurence Danober
Iuliana Botez-Pop
Pierre Lestage
Bernard Pirotte
Jette S. Kastrup
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Citations (26)
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