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Kara J. Sedoris

University of Louisville

5

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42

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c-Myc quadruplex-forming sequence Pu-27 induces extensive damage in both telomeric and nontelomeric regions of DNA.

2014 Journal of Biological Chemistry
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Tumor-associated primo vascular system is derived from xenograft, not host

2013 Experimental and Molecular Pathology
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Abstract 743: Pu-27 G-quadruplex induces uncompensated DNA damage response by destabilizing shelterin complex at telomere and non-telomeric region leading to cell death.

2013 Cancer Research
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Abstract 5193: The importance of primo vascular system (PVS) on cancer metastasis and therapeutic intervention: A new dimension of cancer stem cell

2012 Cancer Research
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Abstract 2123: ATM mediated homeostasis of ‘shelterin’ at telomere is compromised by G-quadruplex leading to DNA damage

2012 Cancer Research
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