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Mingxiang Liao

Takeda Pharmaceutical Company

31

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443

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Pharmacokinetics and safety of rucaparib in patients with advanced solid tumors and hepatic impairment.

2021 Cancer Chemotherapy and Pharmacology
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A phase 1, open-label, drug-drug interaction study of rucaparib with rosuvastatin and oral contraceptives in patients with advanced solid tumors.

2021 Cancer Chemotherapy and Pharmacology
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Prediction of Transporter-Mediated Rosuvastatin Hepatic Uptake Clearance and Drug Interaction in Humans Using Proteomics-Informed REF Approach.

2020 Drug Metabolism and Disposition
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P129 - In-vivo transporter-mediated hepatic clearance of rosuvastatin in humans could be better predicted using transporter-expressing cells than hepatocytes

2020 Drug Metabolism and Pharmacokinetics
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Evaluation of in vitro absorption, distribution, metabolism, and excretion and assessment of drug-drug interaction of rucaparib, an orally potent poly(ADP-ribose) polymerase inhibitor

2020 Xenobiotica
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Evaluation of absorption, distribution, metabolism, and excretion of [14C]-rucaparib, a poly(ADP-ribose) polymerase inhibitor, in patients with advanced solid tumors

2019 Investigational New Drugs
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Comparison of uptake transporter functions in hepatocytes in different species to determine the optimal model for evaluating drug transporter activities in humans

2019 Xenobiotica
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Does plasma membrane and total transporter abundance differ between suspended, plated, sandwich culture hepatocytes and human liver tissue?

2019 Drug Metabolism and Pharmacokinetics
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PET Imaging of [ 11 C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporine A

2019 Clinical Pharmacology & Therapeutics
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Can transporter-expressing cells predict rosuvastatin uptake clearance in suspended or plated human hepatocytes?

2019 Drug Metabolism and Pharmacokinetics
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