Identifying context appropriate strategies for introducing microbicides into different settings in order to maximise impact

Background: This study uses epidemiological and economic modelling to estimate the impact of alternative potential strategies for microbicide introduction into two communities in contrasting settings with different behavioural and epidemiological profiles: (1) a southern Indian community (where the HIV epidemic is mostly concentrated among high-risk groups), and (2) an urban community in South Africa (with a generalised HIV epidemic).