Correlation among dermoscopy, confocal reflectance microscopy, and histologic features of melanoma and basal cell carcinoma collision tumor.

Reflectance confocal microscopy (RCM) is a noninvasive imaging technique that has been shown to enhance secondary evaluation of melanocytic lesions by allowing for in vivo visualization of microscopic structures and cellular details of the epidermis and superficial dermis at almost histologic resolution. RCM has been used to image various skin conditions, including benign and malignant pigmented lesions, amelanotic melanoma, BCC, and actinic keratosis.