Factors Relating with Fertilization Failure in Conventional IVF-ET Cycles

Objective To analyze the factors relating with fertilization failure in conventional IVF cycles. Methods The total fertilization failure rate of 2 429 IVF cycles from January 2011 to May 2012 in the Reproductive Centre of the Women and Children Hospital of Jiangxi Province were retrospectively analyzed. Risk factors were identified by univariate and multivariate logistic regression analyses. Results The total fertilization failure rate of conventional IVF-ET rate was 5.7% (139/2 429). The percentage of morphologically normal sperm (11.1 ± 5.8% vs 13.4 ± 5.3%), progressive motility (47.4 ± 10.5% vs 50.1 ± 8.6%), percentage of couple primary infertility (79.1% vs 44.3%), percentage of female primary infertility (69.1% vs 36.3%), percentage of male primary infertility (74.8% vs 41.7%), percentage of without oviduct obstruction patients (30.2% vs 13.6%) and percentage of couples primary infertility (79.1% vs 44.3%) of the fertilization failure patients were significantly different from those of the fertilized patients (P Conclusion Patients with low percentage of morphologically normal sperm (