997 Comparing patient characteristics and survival rates in ovarian cancer patients presenting from (GP) and(ED) in the university hospitals of Leicester

Introduction/Background* There is limited data exploring whether the mode of referral of ovarian cancer patients will affect the patient’s overall survival. The aim of the study is to explore the differences in patients’ characteristics in ovarian cancer patients presenting to the GP and ED and comparing their 1-year, 3-year and 5-year overall survival in general and in each stage. Methodology A retrospective analysis performed in the University Hospitals of Leicester from 1st of January 2015 to the 1st of January 2020 recruiting 298 patients with ovarian cancer: 197 were referred from GP and 101 were referred from ED. Statistical analysis of the patients’ characteristics were done and the overall survival rates were compared in both groups using Kaplan Meier Curves. Result(s)* There is no statistical difference in the demographic characteristics between the ovarian cancer patients referred from GP and ED. The 1-year, 3-year and 5-year overall survival rates in ovarian cancer patients were 85.8%, 64.2% and 53.4% respectively when referred from GP; however, it was 81.1%, 67.3% and 57.8% when referred from ED. The overall survival rates between the two groups did not show statistical difference (p=0.948). When comparing the overall survival rates in each stage of ovarian cancer, there was no statistical significant difference between the 1- year, 3-year and 5-year overall survival in ovarian cancer patients referred from GP and ED with ovarian cancer in stage 1 (p=0.262), stage 2 (p=0.350), stage 3 (p=0.906) and stage 4 (p=0.224). Conclusion* The mode of referral of ovarian cancer patients does not affect the overall survival for any FIGO stage (p=0.948). Women with ovarian cancer, at presentation, irrespective of the mode of referral should be assessed by the gynaecological oncology team to offer timely treatment with initial surgery or neo-adjuvant chemotherapy.