Comparison of three molecular methods to detect mutations in KRAS, NRAS, BRAF and PIK3CA in metastatic colorectal cancer (mCRC).

Cristina Santos,Rocio Garcia-Carbonero,Pilar Alfonso,Daniel Azuara,Mar Varela,Valentín Navarro Pérez,Alfredo Carrato,Elena Elez,M.Auxiliadora Gomez-España,Ferran Losa,Clara Montagut,Bartomeu Massuti,Jose Luis Manzano,J.M. Vieitez,M. Valladares,Xavier Sanjuan,Gabriel Capellá,E. Aranda,Josep Tabernero,Ramon Salazar

Comparison of three molecular methods to detect mutations in KRAS, NRAS, BRAF and PIK3CA in metastatic colorectal cancer (mCRC).

2016

3559Background: Mutational analysis of RAS in mCRC has showed an improvement in patient (pts) selection for anti-EGFR drugs. The standard techniques (Techs) have an analytical sensitivity (Sns) of ...

Keywords:

Colorectal cancer
Neuroblastoma RAS viral oncogene homolog
KRAS
Pathology
Medicine
Oncology
in patient
mutational analysis
Internal medicine

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