Őrszemnyirokcsomó-státus és hónalji blokkdissectio az emlőrák sebészi ellátásában | Sentinel lymph node status and axillary lymph node dissection in the surgical treatment of breast cancer

2014 
Az axillaris blokkdissectio emlőrakos betegeknel tradicionalisan egy terapias es stadiummeghatarozo műtet, amely soran a honalji nyirokcsomokat szelektivitas nelkul tavolitjak el. A mai napig ellentmondasos annak a megitelese, hogy a honalji nyirokcsomok eltavolitasanak van-e tulelest befolyasolo szerepe. Az őrszemnyirokcsomo-biopszia soran a regionalis attetek legvaloszinűbb helyet, a primer tumorral direkt osszekottetesben allo nyirokcsomokat tavolitjak el, ami lehetőseget ad reszletesebb stagingvizsgalatokra, es lehetőve teszi a honalji blokkdissectio szelektivve tetelet, azon betegeknel indikalva azt, akiknel ugy veljuk, ennek haszna lehet. Kezdetben a tanulasi fazis alatt minden betegnel, majd csak az őrszemnyirokcsomoban attetes betegeknel vegeztek blokkdissectiot, de ujabban bizonyos korulmenyek kozott, minimalis erintettseg mellett akar őrszemnyirokcsomo-makrometasztazisok eseten is biztonsagosnak tartjak a blokkdissectio elhagyasat. Jelen kozlemeny a honalj sebeszi kezelesenek valtozasait, az ezek mogott allo evidenciakat es ellentmondasokat, valamint az ezekkel kapcsolatos ajanlasokat foglalja ossze. Orv. Hetil., 2014, 155(6), 203–215. | Axillary lymph node dissection has been traditionally perceived as a therapeutic and a staging procedure and unselectively removes all axillary lymph nodes. There still remains some controversy as concerns the survival benefit associated with axillary clearance. Sentinel lymph node biopsy removes the most likely sites of regional metastases, the lymph nodes directly connected with the primary tumour. It allows a more accurate staging and a selective indication for clearing the axilla, restricting this to patients who may benefit of it. Axillary dissection was performed in all patients during the learning phase of sentinel lymphadenectomy, but later only patients with metastasis to a sentinel node underwent this operation. Currently, even some patients with minimal sentinel node involvement, including some with macrometastasis may skip axillary clearance. This review summarizes the changes that have occurred in the surgical management of the axilla, the evidences and controversies behind these changes, along with current recommendations. Orv. Hetil., 2014, 155(6), 203–215.
    • Correction
    • Source
    • Cite
    • Save
    • Machine Reading By IdeaReader
    0
    References
    2
    Citations
    NaN
    KQI
    []