Abstract 15425: The Novel Late Sodium Current Blocker GS-458967 Suppresses Action Potential Duration Alternans and Early Afterdepolarization in a Transgenic Rabbit Model of Long Qt Syndrome Type 2

Congenital long QT syndrome type 2 (LQT2) is a familial disease, characterized by prolongation of the QT interval and sudden cardiac death caused by polymorphic ventricular tachycardia (PVT) due to...