Enriched blood IgG sialylation attenuates IgG-mediated and IgG-controlled-IgE-mediated allergic reactions

Janina Petry,Johann Rahmöller,Lara Dühring,Gina-Maria Lilienthal,Selina Lehrian,Jana-Sophia Buhre,Yannic C. Bartsch,Alexandra Epp,Hanna B. Lunding,Kelley W. Moremen,Alexei Leliavski,Marc Ehlers

Enriched blood IgG sialylation attenuates IgG-mediated and IgG-controlled-IgE-mediated allergic reactions

2020

Janina Petry
Johann Rahmöller
Lara Dühring
Gina-Maria Lilienthal
Selina Lehrian
Jana-Sophia Buhre
Yannic C. Bartsch
Alexandra Epp
Hanna B. Lunding
Kelley W. Moremen
Alexei Leliavski
Marc Ehlers

Murine blood IgG1, but not IgG2a, sialylation levels attenuate IgG-mediated and IgG-controlled IgE-mediated allergic reactions by enhancing the expression of the IgG inhibitory Fcγ receptor IIB on immune cells, accordingly, human blood IgG sialylation levels correlate with FcγRIIB expression.

Keywords:

ige mediated
Medicine
Immunology

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations