Co-isolation and analysis of extracellular vesicle (EV)-associated DNA and cell free DNA (cfDNA) to improve the diagnostic and prognostic value of circulating BRAF V600E in metastatic melanoma patients.

Davide Zocco,Simona Bernardi,Mauro Novelli,Natasa Zarovni,Francesco Martino Carpi,Ottavia Malavenda,Pietro Quaglino,Domenico Russo,Antonio Chiesi,Maria Teresa Fierro

Co-isolation and analysis of extracellular vesicle (EV)-associated DNA and cell free DNA (cfDNA) to improve the diagnostic and prognostic value of circulating BRAF V600E in metastatic melanoma patients.

2018

Davide Zocco
Simona Bernardi
Mauro Novelli
Natasa Zarovni
Francesco Martino Carpi
Ottavia Malavenda
Pietro Quaglino
Domenico Russo
Antonio Chiesi
Maria Teresa Fierro

e21564Background: Detection of BRAF V600E on cell free tumor DNA (cfDNA) is emerging as a promising means to improve patient’s stratification or enable BRAFi therapy monitoring in a minimally invas...

Keywords:

Cell-free fetal DNA
Melanoma
DNA
Extracellular vesicle
Cancer research
BRAF V600E
Pathology
Medicine
metastatic melanoma
therapy monitoring
cell free

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