A series of ovarian clear cell and endometrioid carcinoma and their association with endometriosis.

Aim: To present our department's experience with clear cell carcinoma and endometrioid carcinoma of the ovary, paying particular attention to their relationship with endometriosis and concomitant endometrial pathology. Method: Retrospective review of case records. Results: From July 1986 to March 1995, II patients with clear cell carcinoma and 20 patients with endometrioid carcinoma of the ovary were treated. Of the patients with clear cell carcinoma, five (45%) had associated endometriosis. One patient (9%) also had endometrial adenomatous hyperplasia. Of the 20 cases of ovarian endometrioid carcinoma, four (20%) had endometriosis present during histopathological examination. Six patients (30%) had concomitant endometrial pathology (five cases of endometrial carcinoma and one with adenomatous hyperplasia). Conclusion: Our series shows that the clear cell ovarian carcinoma may often be associated with endometriosis, more so than the endometrioid type of ovarian carcinoma. However, the patient with ovarian endometrioid carcinoma may also harbour a concurrent endometrial pathology.