Clinicopathological features and prognosis of pregnancy associated breast cancer at Instituto Nacional de Cancerología of Mexico.

e13099Background: Pregnancy-associated breast cancer (PABC) includes breast cancer diagnosed during pregnancy or within one or two years after delivery. PABC is the second most common malignancy diagnosed in pregnancy. There is controversial information about outcomes in this setting. Methods: We conducted a retrospective case-control study to evaluate overall survival (OS) and progresion free survival (PFS) of pregnant versus non-pregnant women with breast cancer, matched for age, inmunohistochemical subtype and stage of disease. Results: Median age was 35 years, there were no differences between cases and controls regarding clinical stage, tumor grading, IHC subtype (p = 1.0), Ki67 and histological type. Highlight that 31% were triple negative. Cases and controls were followed over 48 months. Kaplan–Meier survival showed no significant difference in OS and PFS between cases and controls (p = 0.892 and 0.121 respectivily). But if we analized the population by the time breast cancer takes place, the perce...