Lennert's Lymphoma—Pathological and Immunological Studies in a Patient with Widespread Skin Involvement

A 21-year-old male presented with a widespread skin infiltration characterized by irregularly elevated blue-red plaques, generalized lymphadenopathy and enlarged parotid glands. Histological examination of the skin showed the characteristics of Lennert's lymphoma, as did the lymph nodes and parotid glands. Immunological studies on lymph node tissue revealed normal amounts of B- and T-cells. The B-cells were polyclonal. The T-cells showed functional impairment in culture. Treatment with prednisone resulted in complete disappearance of all tumour manifestations within 6 weeks.