A New Versatile Protocol for the Synthesis ofIndazolophthalazinetriones
2021
Potassium hydrogen sulfate (KHSO4) and
trifluoromethanesulfonic acid
(CF3SO3H) were separately used
as efficient catalysts for the one-pot three-component synthesis of a series of
indazolophthalazinetriones from various aldehydes, dimedone, and
2,3-dihydrophthalazine-1,4-dione at 80°C under solvent-free conditions in good
to excellent yields. It was found that trifluoromethanesulfonic acid is a more
efficient catalyst than potassium hydrogen sulfate since
CF3SO3H is a stronger acid
than KHSO4, and the corresponding intermediate will
probably be formed at a higher rate and be more stable.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
30
References
0
Citations
NaN
KQI