Abstract 9369: Nanoparticle-mediated Delivery of TT-10 Promotes Cardiomyocyte Proliferation and Myocardial Repair

Wangping Chen,Danielle Pretorius,Yang Zhou,Jianyi Zhang

Abstract 9369: Nanoparticle-mediated Delivery of TT-10 Promotes Cardiomyocyte Proliferation and Myocardial Repair

2021

Wangping Chen
Danielle Pretorius
Yang Zhou
Jianyi Zhang

The pharmaceutical product TT-10 increases cardiomyocyte proliferation and survival by upregulating nuclear levels of Yes-associated protein (Yap) and the expression of Yap-targeted genes. When eva...

Keywords:

Cardiomyocyte proliferation
Heart failure
Medicine
Myocardial infarction
cardiac regeneration
Gene
Cardioprotection
Cell biology

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