Etiology and mechanism of colonic transit dysfunction

Sicknesses caused by colonic transit dysfunction are commonly seen in clinical practice.The transit dysfunction of the colon has been studied in recent decades on the primary abnormalitie,the secondary damage of the colon enteric nervous system,the distribution of Cajal interstitial cells with the c-kit protein expression of its surface,the damage of smooth muscle by autoimmune,the absorption of water by colon,viral infections and the genetic aspects. Key words: Colonic transit dysfunction;  Enteric nervous system;  Smooth muscle;  Cajal interstitial cells