MUCOSAL LEISHMANIASIS: A CASE REPORT OF AN EXTENSIVE AND MORIFORM LESION

Mucosal leishmaniasis is a chronic infection that affects the upper respiratory tract or oral mucosa caused by protozoan parasites of the genus Leishmania. A 70-year-old man presented with oral opening limitation and presence of a moriform lesion involving palate and oropharynx. The patient reported a history of pharyngeal cancer 3 years earlier. Incisional biopsy was performed, and the histologic analysis showed mononuclear inflammatory infiltrate with macrophage vacuoles containing scarce rounded microstructures suggestive of amastigotes. However, Giemsa staining and immunohistochemistry were negative. The patient returned and reported the death of his dogs recently. Dermatologic examination revealed ulcerated lesion under a beard in the region of the chin. The patient was referred to the infectious disease service, and the skin lesion biopsy showed aspects compatible with leishmaniasis. With the diagnosis of mucocutaneous leishmaniasis, the patient is still receiving treatment at the infectious disease service. Support: FAPEMIG (APQ01122/14)