Midterm Reversible Failure in Trabeculectomies With Adjunctive Mitomycin-C

. BACKGROUND AND OBJECTIVES: Trabeculectomies usually fail early ( 6 months) when no antifibrotic agent is used. Failure is uncommon during the midterm period, between 3 weeks and 6 months. The purpose of this study is to verify the incidence of failure of trabeculectomies with mitomycin-C (MMC) during the midterm period and to evaluate the safety and efficacy of laser suture lysis (LSL) for reversing it. . PATIENTS AND METHODS: The authors reviewed the records of 130 consecutive patients who underwent trabeculectomy with adjunctive MMC. . RESULTS: Fourteen patients (15 eyes) had increased intraocular pressure (TOP), between 21 and 185 days (median 41 days). LSL was effective in decreasing the IOP to acceptable levels in 10 (66.6%) of the 15 eyes. No complications related to LSL were noticed. . CONCLUSION: The reversibility of midterm failure seems to be a unique feature of trabeculectomies with MMC.