Early assessment of tumor response to JAC106, an anti-tubulin agent, by 3′-deoxy-3′-[18F]fluorothymidine in preclinical tumor models

Seung Jin Lee,Hye Young Kang,Seog-Young Kim,Jin Hwa Chung,Seung Jun Oh,Jin-Sook Ryu,Sung-Bae Kim,Jong Soon Kang,Song-Kyu Park,Hwan-Mook Kim,Myung-Hwa Kim,Dae Hyuk Moon

Early assessment of tumor response to JAC106, an anti-tubulin agent, by 3′-deoxy-3′-[18F]fluorothymidine in preclinical tumor models

2011

Seung Jin Lee
Hye Young Kang
Seog-Young Kim
Jin Hwa Chung
Seung Jun Oh
Jin-Sook Ryu
Sung-Bae Kim
Jong Soon Kang
Song-Kyu Park
Hwan-Mook Kim
Myung-Hwa Kim
Dae Hyuk Moon

Purpose We determined whether [18F]fluorothymidine (FLT) positron emission tomography (PET) can detect early effects on tumor proliferation of JAC106, a new anti-tubulin agent.

Keywords:

Medicine
Radiology
Positron emission tomography
Tubulin
18f fluorothymidine
tumor response

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