Nonclinical safety assessment of AMG 553, an investigational anti-FLT3 CAR-T therapy.
2019
7032Background: FMS-like tyrosine kinase 3 (FLT3) is a tyrosine-protein kinase involved in hematopoiesis. In acute myeloid leukemia (AML), higher FLT3 transcript levels, independent of the presence...
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