Approach to Fertility Preservation in Adult and Pre-pubertal Males

Recent advances in medicine have led to ever increasing number of pre-pubertal and adult males surviving cancer treatment. This has increased the need to improve the existing technology for cryopreservation of gametes and search for new fertility preservation options. As of today, only sperm cryopreservation is considered accepted standard clinical practices. Fertility preservation options in pre-pubertal males are still experimental. Cryopreservation of testicular tissue and spermatogonial stem cell transplantation should only be offered within IRB-approved clinical protocol after thorough counseling of patients and their family members as there are still many unresolved issues related to these technologies.