Disinfection Practice of Glutaraldehyde in Hospital

Glutaraldehyde, a disinfectant of HB virus approved by WHO, on spot use in hospital, mar be likely to cause a cross-contamination with other disinfectants and its content and potency may possibly be decreased to some degree when used for inactivation of HBs antigen positiveblood. The following tests were performed.(1) 2% Glutaraldehyde and some other disinfectant used in a hospital were combined at theratio of 99: 1 or 90: 1. Little reduction was observed both in the content and the disinfection, potency.(2) 2% Glutaraldehyde was mixed with a blood at the ratio of 9: 1 and8: 2. No reduction was seen in the duration of potency when compared with each control. In the mixtures at theratio of 7: 3, 6: 4 and 5: 5, the potency lasted longer than that of each control.It was concluded that a notable decrease in the disinfection potency is not caused unless the mixed volume of blood exceeds 10%.