A kind of preparation method of vitamine A acetate

A kind of preparation method of vitamine A acetate provided by the present invention, comprises the following steps：(1) in alkaline conditions, 3 methyl, 4 oxygen, 2 butylene, 1 base acetate (abbreviation C5 aldehydo-esters) and Medronate tetra-ethyl ester occur condensation reaction and obtain intermediate C6 phosphates (entitled 5 (p diethylaminobenzoic acid ester group) 32,4 hexadiene of methyl, 1 acetate of chemistry)；(2) C6 phosphates carry out indexing in alkaline conditions, add C14 aldehyde (entitled 2 methyl 4 (2 of chemistry, 6,6 trimethyl, 1 cyclohexene, 1 base) 3 butylene, 1 aldehyde) Wittig Horner condensation reactions generation vitamine A acetate occurs.The preparation method raw material are easy to get, synthetic route is short, safe operation, suitable for industrial production.