HIGH PREVALENCE OF PERIODONTAL DISEASE IN INDIVIDUALS WITH NEUROFIBROMATOSIS 1

Objective: Investigate the prevalence of periodontal disease in individuals with neurofibromatosis 1 (NF1). Study design: This study was conducted on 42 Brazilian individuals diagnosed with NF1; their ages ranged from 18 to 77 years (mean age, 40 years). Of these, 72% (32 out of 42) were female and 28% (10 out of 42) were male. All participants were subjected to anamnesis, oral exam, measurement of oral hygiene index, tongue coat index, community periodontal index (CPI), and periodontal loss of attachment index. The results were compared with a sex- and age-paired control group. Results: According to the CPI, 37% of individuals with NF1 had gingival bleeding and 68% had periodontal loss of attachment of 4 to 5 mm. Compared to the control group, there was a significant statistical difference in CPI (P = .013) and periodontal loss of attachment (P = .001). Comparing the periodontal indexes of patients with NF1 and oral hygiene, there was an association with poor oral hygiene and loss of periodontal insertion (P