Experimental Study on the Efficacy of Intrahepatic Arterial and Portal Venous Infusion of Anticancer Drugs to Inhibit the Growth of Portally Inoculated VX-2 Carcinoma

To evaluate the efficacy of intraarterial and portal venous infusion of anticancer drugs to inhibit the growth of portally inoculated VX-2 tumor cells (1×107), adriamycin (lmg/kg) was administered into the hepatic artery (HA) and portal vein (PV) at 3’rd, 5’th, 7th days (group 1), immediately, 2’nd, 4’th days (group 2) after tumor cell inoculation respectively, and no adriamycin was administered as the control group. The number of tumor nodules on the whole liver surface at three weeks after tumor inoculation in the control, HA. group 1, PV. group 1, HA. group 2 and PV. group 2 was 409±138.5, 46.3±42.4,130.7±77.7, 0.0±0.0, and 10.5±5.7 respectively.