Raptor localization predicts prognosis and tamoxifen response in estrogen receptor-positive breast cancer

Josefine Bostner,Anya Alayev,Adi Y. Berman,Tommy Fornander,Bo Nordenskjöld,Marina K. Holz,Olle Stål

Raptor localization predicts prognosis and tamoxifen response in estrogen receptor-positive breast cancer

2018

Josefine Bostner
Anya Alayev
Adi Y. Berman
Tommy Fornander
Bo Nordenskjöld
Marina K. Holz
Olle Stål

Purpose Deregulated PI3K/mTOR signals can promote the growth of breast cancer and contribute to endocrine treatment resistance. This report aims to investigate raptor and its intracellular localization to further understand its role in ER-positive breast cancer.

Keywords:

Breast cancer
Cancer research
Intracellular localization
PI3K/AKT/mTOR pathway
Tamoxifen
Endocrine system
Estrogen receptor
Oncology
Internal medicine
Medicine
luminal a
treatment resistance

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