Malignant Lymphoma and Multiple Myeloma

Lymphomas are malignant diseases arising from uncontrolled proliferation of lymphatic cells. Such cells are primarily located in lymph nodes; thus, enlargement of lymph nodes is the most common symptom. Because of the wide distribution of lymphatic tissue throughout the body, lymphomas may also arise in extranodal and extralymphatic sites such as brain, lungs, stomach, testes, and bones. Extralymphatic tissues may be involved by contiguous extension of disease from nodal sites (E lesions) or by hematogenous spread in advanced stages.