Efecto del consumo de jugo de tomate de árbol ( Cyphomandra betacea ) sobre el perfil lipídico y las concentraciones de glucosa en adultos con hiperlipidemia, Ecuador.

2016 
En este trabajo se evaluo el efecto del consumo del jugo de tomate de arbol (Cyphomandra betacea) sobre parametros nutricionales y bioquimicos en 54 voluntarios (44 mujeres y 10 hombres) con edades 45±8 anos de Ecuador. Al inicio se les realizo una evaluacion nutricional y bioquimica, luego se les invito a consumir el jugo (100g de fruto en 150 ml de agua) diariamente durante 6 semanas. Finalizado este tiempo, se procedio a realizar la evaluacion nutricional y bioquimica nuevamente. La evaluacion nutricional determino 67% de obesidad abdominal. Disminuyendo a 53% despues del consumo del jugo de tomate de arbol. El 87% de los voluntarios antes del tratamiento, mostraron hipercolesterolemia; 40,7% y 46,3% tenian los trigliceridos y el LDL elevados y 18,5% valores de glucosa entre 98-130mg/dL. Valores que disminuyeron significativamente en este grupo despues de la toma del jugo En general, tanto en voluntarios con y sin sobrepeso se observo disminucion significativa de colesterol total, LDL y glucosa; sin cambios significativos en los valores de HDL. El consumo del jugo no afecto la actividad de las enzimas alanina-aminotransferasa ni aspartato-aminotransferasa, tampoco las concentraciones de creatinina, urea y acido urico; ni la presion arterial, demostrando que no afecta la funcion hepatica ni renal. Estos resultados indican que el consumo del jugo de tomate de arbol, durante seis semanas, parece ejercer un efecto hipolipemiante y moduladora en el metabolismo de la glucosa y colocan a C betacea como uno de los frutos andinos con alto potencial nutraceutico. Sin embargo, estos aspectos deben ser investigados con mas detalles.(AU) In this work the effect of consumption of tree tomato juice (Cyphomandra betacea) was evaluated on nutritional and biochemical parameters in 54 volunteers (44 women and 10 men) aged 45 ± 8 years-Ecuador. A nutritional and biochemical evaluation was performed in volunteers; then they were invited to drink tree tomato juice (100g of fruit in 150 ml of water) daily for 6 weeks. Finished these 6 weeks, volunteers were nutritional and biochemical evaluated again. 67% abdominal obesity was found, decreasing at 53% after drinking the established dosage of juice. 87% of the volunteers before treatment, showed hypercholesterolemia, 40.7% and 46.3% had hypertriglyceridemia and elevated LDL, respectively and 18.5% glucose concentrations between 98-130 mg/dL. These values decrease significantly in this group after drinking tomato juice. In general, Total Cholesterol, LDL and glucose concentrations decrease significantly after drinking tree tomato juice in all the voluntaries with or without overweight. There is no change in HDL concentrations. The consumption of tree tomato juice did not affect the activity of alanine aminotransferase or aspartate aminotransferase enzymes either creatinine, urea and uric acid concentrations, neither blood pressure suggesting that does not affect renal or liver function. These results indicate that consumption of tree tomato juice for six weeks appears to have a lipid-lowering and modulating effect on glucose metabolism, suggesting C betacea as one of the high Andean fruits nutraceutical potential. However, this issue should be investigated in more detail.(AU)
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