Pharmacokinetics, metabolism, biodistribution, radiation dosimetry, and toxicology of 18F-fluoroacetate ( 18F-FACE) in non-human primates

Introduction To facilitate the clinical translation of 18F-fluoroacetate (18F-FACE), the pharmacokinetics, biodistribution, radiolabeled metabolites, radiation dosimetry, and pharmacological safety of diagnostic doses of 18F-FACE were determined in non-human primates.