DPP4 inhibition mitigates ANG II-mediated kidney immune activation and injury in male mice.

Ravi Nistala,Alex Meuth,Cassandra Smith,Jianzhong An,Javad Habibi,Melvin R. Hayden,Megan S. Johnson,Annayya R. Aroor,Adam Whaley-Connell,James R. Sowers,Susan R McKarns,Shawn B. Bender

DPP4 inhibition mitigates ANG II-mediated kidney immune activation and injury in male mice.

2021

Ravi Nistala
Alex Meuth
Cassandra Smith
Jianzhong An
Javad Habibi
Melvin R. Hayden
Megan S. Johnson
Annayya R. Aroor
Adam Whaley-Connell
James R. Sowers
Susan R McKarns
Shawn B. Bender

Recent evidence suggests that DPP4 inhibition with saxagliptin (Saxa) is renoprotective in co-morbid conditions associated with activation of the renin-angiotensin-aldosterone system (RAAS), such a...

Keywords:

Endocrinology
Saxagliptin
Kidney
Internal medicine
male mice
immune activation
Immune system
Medicine
Albuminuria
Angiotensin II
immune mechanisms

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