HCV/HBV infection in Italian patients (pts) with solid tumor candidates for chemotherapy (CT).

e12521 Background: There are few studies dealing with the prevalence of chronic infection by HBV or HCV in Italian pts candidated to CT for solid tumors and on the episodes of hepatitis reactivation during the CT. Methods: Pts referred to S.Orsola-Malpighi Hospital Medical Oncology Unit undergo to blood tests (BT) that include a screening for HBV and HCV infection by testing the positivity for HbsAg and anti-HCV. We examined the records of 564 consecutive new pts from January to December 2012. Pts who performed at least 1 BT were considered elegible: 479/564 (84.9%). Results: Pts screened: 435(90.8%) HbsAg, 397(82.9%) anti-HCV and 397 (82.9%) for both. 24 pts were found positive: 9 (1.9%) HBsAg+, 14 (3.5%) anti-HCV+, 1 (0.3%) HBsAg+/anti-HCV+. Males 16 (66.7%). Primary tumors: 9 (37.5%) liver, 4 (16.7%) lung, 3 (12.5%) head-neck, 3 (12.5%) colon, 2 (8.3%) bladder, 1 (4.2%) anus, 1 (4.2%) breast, 1 (4.2%) gastric, 1 (4.2%) skin. 3/24 pts (12.5%) with abnormal liver function tests at baseline were not treat...