Folliculitis in Down's syndrome

Summary Twenty-two male and 20 female adults with Down's syndrome were examined. Ten of the men and two of the women had a folloicular rash consistent with Malassezia folliculitis. Oral itraconazole treatment produced a significant improvement in the rash. Accompanied by a decrease in the skin Malassezia count. Clinical relapse occurred when therapy was discontinded, and was accompanied by return of the Malassezia yeasts.