Clinical characteristics of patients with cervical vascular pseudoaneurysm after radiotherapy for nasopharyngeal carcinoma

: Objective:The aim of this study is to analyze the clinical features of the pseudoaneurysm of the cervical vascular in patients with nasopharyngeal carcinoma after radiotherapy, and to summarize the clinical signs of patients with cervical vascular aneurysm, and to provide a basis for improving the success rate of treatment. Method:Patients with hemorrhage disease were treated by digital subtraction angiography （DSA） after radiotherapy for nasopharyngeal carcinoma are included. According to the presence or absence of pseudoaneurysm （PSA）, patients are divided to pseudoaneurysm group （PSA group） and non-pseudoaneurysm group（non-PSA group）, analysis of gender, age, presence or absence of tumor recurrence, presence or absence of recurrent radiotherapy, history of nasopharyngeal surgery after radiotherapy, needed to open the airway before the interval therapy, time to the end of radiotherapy. Result:The rate of tumor recurrence was 80% （12/15） in patients with pseudoaneurysm and 60%（9/15） in recurrent radiotherapy, which was significantly higher than that in patients with non-pseudular aneurysms. The average time to the end of radiotherapy is 36.5 months in patients with pseudoaneurysm, significantly shorter than non-pseudoaneurysm patients（106.7 months）. Conclusion:The high-risk clinical features of patients with cervical vascular pseudoaneurysm include: ①recurrence of nasopharyngeal carcinoma; ②history of recurrent radiotherapy; ③interval time is shorter between the hemorrhage and the end of radiotherapy, usually taking place within a few months to two years after recurrent radiotherapy. Patients with the above characteristics need to be screened early, and the DSA should be used as early as possible to confirm the cervical vascular condition and effectively control the hemorrhage.