СОСТОЯНИЕ СПЕРМАТОГЕНЕЗА И АНТИОКСИДАНТНОЙ АКТИВНОСТИ ЭЯКУЛЯТА У МОЛОДЫХ БЕСПЛОДНЫХ МУЖЧИН С ПОСТПУБЕРТАТНЫМ ВИСЦЕРАЛЬНЫМ ОЖИРЕНИЕМ И НЕОТЯГОЩЕННЫМ АНДРОЛОГИЧЕСКИМ АНАМНЕЗОМ

Background : Taking into account a common development of a visceral obesity at men, research of its influence on a spermatogenesis and antioxidative activity of an ejaculate is actual. Aims : Assessments of spermatogenesis and antioxidative activity of ejaculate in young men with post pubertal visceral obesity and normal andrological anamnesis in comparing with healthy men. Materials and methods : 80 men with post pubertal and nutritional visceral obesity in the age of until 30 years and 30 healthy men have been included in cross-section research. The assessments of waist circumference, levels of gonadotropins and total testosteron, antioxidant activity of an ejaculate, its electronic-microscopic examination was carried spent. Statistically significant counted differences between groups at p <0.05. Results : In young men with post pubertal visceral obesity and normal andrological anamnesis the spermatogenesis was significantly worse in comparing with healthy men. These differences were were significant for waist circumference more more then 98 cm. Antioxidative activity of ejaculate in men with visceral obesity also was significantly lower in comparing with healthy men. The maximal expressiveness of sperm pathogenetic disorders was in men with waist circumference more then 102 cm. Conclusions : In young men with post pubertal visceral obesity and normal andrological anamnesis the spermatogenesis is worse compared to healthy men. If the waist circumference less than 102 cm, the spermatogenesis is normal in most cases, but antioxidant activity of an ejaculate is pathological and mediated through oxidative stress.