DNA/europium ion interaction by matrix-assisted laser desorption time-of-flight mass spectrometry

The interaction of DNA and lanthanide ions using Matrix assisted laser desorption time of flight mass spectrometry. 2', 4', 6' hydroxy acetophenone was the matrix used, and Europium chloride was the lanthanide salt used to interact with Adenine and Guanine containing synthetic oligonucleotides. The MALDI analysis permitted the detection of DNA/Europium adducts and also provided information on the stoichiometry of the interaction.© (1997) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.