Standard or Specific Skin Patch Test Series? Results of 615 patients with a pre-diagnosed of Allergic Contact Dermatitis. Standart Test mi, yoksa Özel Deri Yama Testi Serisi mi? Allerjik Kontakt Dermatit Ön Tanısı alan 615 Hastanın Sonuçları

ABSTRACT Objective The incidence of allergic contact dermatitis (ACD) has increased especially in modern and urbanized communities in recent years, just like other allergic diseases. The skin patch test is the gold standard test to identify allergens. The study aims to assess the results of patients who are considered to be diagnosed with ACD and underwent the European Standard Patch Test and compare them with other studies. Methods A total of 615 patients demographics data and patch test results were evaluated retrospectively. Chi-square and Fisher’s exact tests were used for statistical evaluation. Results Of the 615 patients who underwent skin patch testing, 430 (70%) were female and 185 (30%) were male. The mean age was 40.4 ± 12.9 years. No positive reactions were detected in 483 (78.6%) of 615 patients. Nickel sulfate (10.9%), balsam of Peru (3.9%), cobalt chloride (3.2%), potassium dichromate (%2.9) and methyldibromo glutaronitrile (%2.4) were the five most common allergens that caused ACD. Of the 30 allergens in the skin patch test series, 18 had a positive reaction rate was below 1%. Conclusion Performing new skin patch tests with fewer allergens specific to the country and individuals, based on local experiences and patient history, can reduce healthcare costs and risk of patients’ new and unnecessary sensitizations. Standart Test mi, yoksa Ozel Deri Yama Testi Serisi mi? Allerjik Kontakt Dermatit On Tanisi alan 615 Hastanin Sonuclari Amac Allerjik kontakt dermatit (ACD) insidansi son yillarda, tipki diger allerjik hastaliklar da oldugu gibi ozellikle modern ve kentlesmis topluluklarda artmistir. Deri yama testi allerjenleri belirlemek icin altin standart testtir. Bu calismanin amaci AKD tanisi dusunulen ve Avrupa Standart Seri Yama Testi uygulanan hastalarin sonuclarini degerlendirmek ve diger calismalarla karsilastirmaktir. Yontem Toplam 615 hastanin demografik verileri ve yama testi sonuclari retrospektif olarak degerlendirildi. Istatistiksel degerlendirme icin Ki-kare ve Fisher kesin testi (Fisher's exact test) kullanildi. Bulgular Deri yama testi yapilan 615 hastanin 430'u (% 70) kadin, 185'i (% 30) erkekti. Hastalarin yas ortalamasi 40.4 ± 12.9 yil idi. 615 hastanin 483'unde (% 78.6) pozitif reaksiyon saptanmadi. Nikel sulfat (% 10.9), Peru balsami (% 3.9), kobalt klorur (% 3.2), potasyum dikromat (% 2.9) ve metildibromo glutaronitril (% 2.4) AKD'e neden olan en yaygin bes alerjendi. Deri yama testi serisinde bulunan 30 allerjenden 18’i % 1'in altinda pozitif reaksiyon verdi. Sonuc Ulke ve kisilere ozel, bolgesel tecrube ve hasta hikayesine dayali, daha az allerjen iceren yeni deri yama testi serileri uygulamak, saglik giderlerini ve hastalardaki yeni ve gereksiz duyarlanma riskini azaltabilir. Anahtar kelimeler: Allerjik, kontakt, dermatit, yama, testi